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1

Inclusion Formation and Toxicity of the ALS Protein RGNEF and Its Association with the Microtubule Network

Di Gregorio, Sonja E., Volkening, Kathryn, Strong, Michael J., Duennwald, Martin L.

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 9.75 MB

2020

2

Growth Assays to Assess Polyglutamine Toxicity in Yeast

Duennwald, Martin L.

Journal:

Journal of Visualized Experiments

Year:

2012

Language:

english

File:

PDF, 203 KB

english, 2012

3

A functional unfolded protein response is required for chronological aging in Saccharomyces cerevisiae

Chadwick, Sarah R., Fazio, Elena N., Etedali-Zadeh, Parnian, Genereaux, Julie, Duennwald, Martin L., Lajoie, Patrick

Journal:

Current Genetics

Year:

2019

Language:

english

File:

PDF, 2.58 MB

english, 2019

4

Chaperone-dependent amyloid assembly protects cells from prion toxicity

Douglas, P. M., Treusch, S., Ren, H.-Y., Halfmann, R., Duennwald, M. L., Lindquist, S., Cyr, D. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 732 KB

english, 2008

5

A Chaperone Pathway in Protein Disaggregation

Cashikar, Anil G., Duennwald, Martin, Lindquist, Susan L.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 838 KB

english, 2005

6

Cellular stress responses in protein misfolding diseases

Duennwald, Martin L

Journal:

Future Science OA

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

7

ChemInform Abstract: Non-Ionic Template Synthesis of Amide-Linked Rotaxanes: Axles with Benzophenone and Cinnamic Acid Units

T. DUENNWALD, A. H. PARHAM, F. VOEGTLE

Journal:

Year:

1998

File:

PDF, 26 KB

1998

8

A network of protein interactions determines polyglutamine toxicity

Duennwald, M. L., Jagadish, S., Giorgini, F., Muchowski, P. J., Lindquist, S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 1.59 MB

english, 2006

9

Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody

Colby, D. W., Chu, Y., Cassady, J. P., Duennwald, M., Zazulak, H., Webster, J. M., Messer, A., Lindquist, S., Ingram, V. M., Wittrup, K. D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 490 KB

english, 2004

10

Effects of a Single Bout of Interval Hypoxia on Cardiorespiratory Control in Patients With Type 1 Diabetes

Duennwald, T., Bernardi, L., Gordin, D., Sandelin, A., Syreeni, A., Fogarty, C., Kyto, J. P., Gatterer, H., Lehto, M., Horkko, S., Forsblom, C., Burtscher, M., Groop, P.-H.

Journal:

Year:

2013

Language:

english

File:

PDF, 334 KB

english, 2013

11

Polyglutamine misfolding in yeast: Toxic and protective aggregation

Duennwald, Martin L.

Journal:

Year:

2011

Language:

english

File:

PDF, 563 KB

english, 2011

12

A Toolbox for Rapid Quantitative Assessment of Chronological Lifespan and Survival in Saccharomyces cerevisiae

Chadwick, Sarah R., Pananos, Athanasios D., Di Gregorio, Sonja E., Park, Anna E., Etedali-Zadeh, Parnian, Duennwald, Martin L., Lajoie, Patrick

Journal:

Year:

2016

Language:

english

File:

PDF, 4.27 MB

english, 2016

13

A functional unfolded protein response is required for chronological aging in Saccharomyces cerevisiae

Chadwick, Sarah R., Fazio, Elena N., Etedali-Zadeh, Parnian, Genereaux, Julie, Duennwald, Martin L., Lajoie, Patrick

Journal:

Current Genetics

Year:

2019

File:

PDF, 2.58 MB

2019

14

RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe

Chung, Christina Z, Jaramillo, Julia E, Ellis, Michael J, Bour, Daniel Y N, Seidl, Lauren E, Jo, David H S, Turk, Matthew A, Mann, Mitchell R, Bi, Yumin, Haniford, David B, Duennwald, Martin L, Heinem

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 3.60 MB

english, 2019

15

Oxidative Stress-induced Aggregation of Keap1 Impairs Nrf2 Regulation

Ngo, Vy, Karunatilleke, Nadun, Song, Zheng, Brickenden, Anne, Krstic, Milica, Choy, Wing-Yiu, Duennwald, Martin

Journal:

Free Radical Biology and Medicine

Year:

2020

File:

PDF, 243 KB

2020

16

Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity

Leach, Michelle D., Kim, TaeHyung, DiGregorio, Sonja E., Collins, Cathy, Zhang, Zhaolei, Duennwald, Martin L., Cowen, Leah E.

Journal:

G3 Genes|Genome|Genetics

Year:

2017

Language:

english

File:

PDF, 1.69 MB

english, 2017

17

A synergistic small-molecule combination directly eradicates diverse prion strain structures

Roberts, Blake E, Duennwald, Martin L, Wang, Huan, Chung, Chan, Lopreiato, Nicholas P, Sweeny, Elizabeth A, Knight, M Noelle, Shorter, James

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 1.89 MB

english, 2009

18

SPIE Proceedings [SPIE SPIE LASE - San Francisco, California (Saturday 21 January 2012)] High-Power Diode Laser Technology and Applications X - A 15-kW fiber-coupled diode laser for pumping applications

Matthews, David G., Kleine, Klaus, Krause, Volker, Koesters, Arnd, Duennwald, Daniel, Pflueger, Silke, Zediker, Mark S.

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

19

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

Duennwald, M. L., Lindquist, S.

Journal:

Genes & Development

Year:

2008

Language:

english

File:

PDF, 775 KB

english, 2008

20

Effects of Supervised Short-Term Exercise Training On Cardiorespiratory Control and Exercise Capacity in Type 2 Diabetes Patients

Duennwald, Tobias

Journal:

Journal of Diabetes & Metabolism

Year:

2014

Language:

english

File:

PDF, 680 KB

english, 2014

21

Effects of a Single Bout of Interval Hypoxia on Cardiorespiratory Control and Blood Glucose in Patients With Type 2 Diabetes

Duennwald, T., Gatterer, H., Groop, P.-H., Burtscher, M., Bernardi, L.

Journal:

Year:

2013

Language:

english

File:

PDF, 171 KB

english, 2013

22

Pharmacological Tuning of Heat Shock Protein 70 Modulates Polyglutamine Toxicity and Aggregation

Chafekar, Sidhartha M., Wisén, Susanne, Thompson, Andrea D., Echeverria, AnaLisa, Walter, Gladis M., Evans, Christopher G., Makley, Leah N., Gestwicki, Jason E., Duennwald, Martin L.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 4.45 MB

english, 2012

23

Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs

Wang, H., Duennwald, M. L., Roberts, B. E., Rozeboom, L. M., Zhang, Y. L., Steele, A. D., Krishnan, R., Su, L. J., Griffin, D., Mukhopadhyay, S., Hennessy, E. J., Weigele, P., Blanchard, B. J., King,

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 691 KB

english, 2008

24

Visualizing tRNA-dependent mistranslation in human cells

Lant, Jeremy T., Berg, Matthew D., Sze, Daniel HW., Hoffman, Kyle S., Akinpelu, Ibukunoluwa C., Turk, Matthew, Heinemann, Ilka U., Duennwald, Martin L., Brandl, Christopher J., O'Donoghue, Patrick

Journal:

Year:

2017

Language:

english

File:

PDF, 2.02 MB

english, 2017

25

Yeast as a model to study protein misfolding in aged cells

Di Gregorio, Sonja E, Duennwald, Martin L

Journal:

FEMS Yeast Research

Year:

2018

Language:

english

File:

PDF, 613 KB

english, 2018

26

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

Lackie, Rachel E., Maciejewski, Andrzej, Ostapchenko, Valeriy G., Marques-Lopes, Jose, Choy, Wing-Yiu, Duennwald, Martin L., Prado, Vania F., Prado, Marco A. M.

Journal:

Frontiers in Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.62 MB

english, 2017

27

Small Heat Shock Proteins Potentiate Amyloid Dissolution by Protein Disaggregases from Yeast and Humans

Duennwald, Martin L., Echeverria, AnaLisa, Shorter, James, Petsko, Gregory A.

Journal:

Year:

2012

Language:

english

File:

PDF, 3.98 MB

english, 2012

28

ChemInform Abstract: Catenanes and Rotaxanes of the Amide Type

F. VOEGTLE, T. DUENNWALD, T. SCHMIDT

Journal:

Year:

1996

File:

PDF, 23 KB

1996

29

ALS Yeast Models—Past Success Stories and New Opportunities

Di Gregorio, Sonja E., Duennwald, Martin L.

Journal:

Frontiers in Molecular Neuroscience

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

30

Sfp1 links TORC1 and cell growth regulation to the yeast SAGA-complex component Tra1 in response to polyQ proteotoxicity

Jiang, Yuwei, Berg, Matthew D., Genereaux, Julie, Ahmed, Khadija, Duennwald, Martin L., Brandl, Christopher J., Lajoie, Patrick

Journal:

Year:

2019

File:

PDF, 8.34 MB

2019

31

A Subset of Calcium‐binding S100 Proteins Show Preferential Heterodimerization

Spratt, Donald E., Barber, Kathryn R., Marlatt, Nicole M., Ngo, Vy, Macklin, Jillian A., Xiao, Yiming, Konermann, Lars, Duennwald, Martin L., Shaw, Gary S.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.54 MB

english, 2019

32

ChemInform Abstract: Enantioselective Synthesis of (S)-2-Hydroxypropanone Derivatives by Benzoylformate Decarboxylase Catalyzed C—C Bond Formation.

Thomas Duennwald, Ayhan S. Demir, Petra Siegert, Martina Pohl, Michael Mueller

Journal:

Year:

2001

File:

PDF, 34 KB

2001

33

Polyglutamine Expanded Huntingtin Dramatically Alters the Genome-Wide Binding of HSF1

Riva, Laura, Koeva, Martina, Yildirim, Ferah, Pirhaji, Leila, Dinesh, Deepika, Mazor, Tali, Duennwald, Martin L., Fraenkel, Ernest

Journal:

Journal of Huntington's Disease

Year:

2012

File:

PDF, 800 KB

2012

34

ChemInform Abstract: Asymmetric Benzoin Reaction Catalyzed by Benzoylformate Decarboxylase.

Ayhan S. Demir, Thomas Duennwald, Hans Iding, Martina Pohl, Michael Mueller

Journal:

Year:

2000

File:

PDF, 28 KB

2000

35

Polyglutamine toxicity in yeast uncovers phenotypic variations between different fluorescent protein fusions

Jiang, Yuwei, DiGregorio, Sonja E., Duennwald, Martin L., Lajoie, Patrick

Journal:

Year:

2016

Language:

english

File:

PDF, 2.66 MB

english, 2016

36

Impaired Heat Shock Response in Cells Expressing Full-Length Polyglutamine-Expanded Huntingtin

Chafekar, Sidhartha M., Duennwald, Martin L., Borchelt, David R.

Journal:

Year:

2012

Language:

english

File:

PDF, 568 KB

english, 2012

37

Effect of Fluorescent Proteins on Fusion Partners Using Polyglutamine Toxicity Assays in Yeast

Jiang, Yuwei, Di Gregorio, Sonja, Albakri, Maram B., Duennwald, Martin L., Lajoie, Patrick

Journal:

Journal of Visualized Experiments

Year:

2018

Language:

english

File:

PDF, 982 KB

english, 2018

38

Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species

Zhao, Yanding, Zurawel, Ashley A., Jenkins, Nicole P., Duennwald, Martin L., Cheng, Chao, Kettenbach, Arminja N., Supattapone, Surachai

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.01 MB

english, 2018

39

A Subset of Calcium‐binding S100 Proteins Show Preferential Heterodimerization

Spratt, Donald E., Barber, Kathryn R., Marlatt, Nicole M., Ngo, Vy, Macklin, Jillian A., Xiao, Yiming, Konermann, Lars, Duennwald, Martin L., Shaw, Gary S.

Journal:

Year:

2019

File:

PDF, 1.54 MB

2019

40

Sfp1 links TORC1 and cell growth regulation to the yeast SAGA-complex component Tra1 in response to polyQ proteotoxicity

Jiang, Yuwei, Berg, Matthew D., Genereaux, Julie, Ahmed, Khadija, Duennwald, Martin L., Brandl, Christopher J., Lajoie, Patrick

Journal:

Year:

2019

Language:

english

File:

PDF, 8.34 MB

english, 2019

41

Ordered Assembly of Heat Shock Proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on Expanded Polyglutamine Fragments Revealed by Chemical Probes

Walter, G. M., Smith, M. C., Wisen, S., Basrur, V., Elenitoba-Johnson, K. S. J., Duennwald, M. L., Kumar, A., Gestwicki, J. E.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.84 MB

english, 2011

42

Flanking sequences profoundly alter polyglutamine toxicity in yeast

Duennwald, M. L., Jagadish, S., Muchowski, P. J., Lindquist, S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 1.42 MB

english, 2006

43

Countering amyloid polymorphism and drug resistance with minimal drug cocktails

Duennwald, Martin L., Shorter, James

Journal:

Year:

2010

Language:

english

File:

PDF, 1017 KB

english, 2010

44

Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

Hoffman, Kyle S., Duennwald, Martin L., Karagiannis, Jim, Genereaux, Julie, McCarton, Alexander S., Brandl, Christopher J.

Journal:

G3 Genes|Genome|Genetics

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

45

ChemInform Abstract: Synthesis of Rotaxane Assemblies.

T. DUENNWALD, R. JAEGER, F. VOEGTLE

Journal:

Year:

1998

File:

PDF, 22 KB

1998

46

Monitoring polyglutamine toxicity in yeast

Martin L. Duennwald

Journal:

Year:

2011

Language:

english

File:

PDF, 336 KB

english, 2011

47

CAG Expansions Are Genetically Stable and Form Nontoxic Aggregates in Cells Lacking Endogenous Polyglutamine Proteins

Zurawel, Ashley A., Kabeche, Ruth, DiGregorio, Sonja E., Deng, Lin, Menon, Kartikeya M., Opalko, Hannah, Duennwald, Martin L., Moseley, James B., Supattapone, Surachai

Journal:

Year:

2016

Language:

english

File:

PDF, 2.58 MB

english, 2016

48

ChemInform Abstract: An Investigation of Phase Transitions in Rust Layers Using Raman Spectroscopy.

DUENNWALD, J., OTTO, A.

Journal:

Year:

1989

File:

PDF, 158 KB

1989

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